Monday, August 13, 2012
Star Tribune: Vaccination Fears Are Only Upping Danger
And you are dumb enough to not realize that every paragraph of that article makes a claim that is a flat out lie. And nothing would be enough for you to realize nor admit to the real truth. Why don't you do a blog page on why children are so sick these days with more doctor visits, chronic disorders, asthma, allergies, autism, learning disorders, ADD/ADHD, diabetes, and cancer than ever in history? Certainly you can find some half baked study that shows some elusive but what you think is a conclusive link to something anything other than the load of vaccines. Polio vaccine never wiped out polio and any more than small pox vaccine ended small pox.
Have you not realized as well that they continue to blame the unvaccinated for the pertussis outbreaks, while it is predominately the vaccinated in those outbreaks? The vaccine has muted the pathogen, and as well caused another non vaccine targeted Bordetella organism – parapertussis, to become more prevalent? Same thing is happening with the oral live polio vaccine in underdeveloped countries, resultant mutation of the vaccine targeted polio virus; and then add to that multple cases of vaccine caused polio paralysis. Measles and mumps outbreaks in the vaccinated; CDC, oh they just didn't have enough boosters. Thats not a success story.
Until you are willing to accept some unbiased information and the real historical account of these vaccines, and actually and in honesty address those issues, Costner, editor; it will get nowhere as to your in denial ignorance on these issues. Large and increasing numbers of people in this world Costner, now know the truth about vaccines; do you think they are all entirely stupid; or are you the one that is entirely sheeple stupid? But of course protecting the money and false credibility of whatever or whoever you are connected to, has nothing to do with it, right?
End of reply:
Here is a reply comment on that same blog page I responded to, but has yet to be published, likely as always it won't be.
Anonymous August 15, 2012 11:54 AM
I can't tell you how many times I've seen ignorant anti-vaccine cranks claim that measles is 'a harmless disease'.
Because that's why a quarter of all measles cases in France have been hospitalized. That's why a quarter of all measles cases in the outbreak in Australia have been hospitalized.
That's why there's been what, a dozen deaths in France since the outbreak began?
Because death is so harmless?
Or does France suddenly not have good hygiene/sanitation? Or are they all malnourished or poverty stricken? Is that why measles is tearing through the unvaccinated (and undervaccinated) population like a brushfire?
They make me want to vomit.
What makes me want to vomit is that you are through your own mislead ignorance presenting a far less than factual picture here.
You should know that they vaccinate in France and as well in Australia. You include no information as to how many of those cases were vaccinated.
Are you claiming that none of those cases were vaccinated or adequately vaccinated? How many boosters would be enough? The facts show that the incidence of measles is known much higher in vaccinated. It is as well a long known fact that if you have been vaccinated for measles such as with the MMR vaccine and you get the measles anyway, that you can have a worse case of measles because of having been vaccinated. Stop the toxic assault with all the endless vaccines on these children's immune systems, and they likely will NOT be hospitalized after acquiring the measles, and will be far less cases going to the hospital. There is not allot a doctor can do for a viral infection, anyway. Give the child some adequate amounts of vitamins D3, A, and C? Better yet advocate for that BEFORE they get sick. But no, they refuse; and in their world, only a chemical drug can cure or prevent disease. What, is the human body short of toxic chemicals and biologic's strained through some monkey kidneys or some other animal based and rancid fluids process? Whats wrong with that picture? What do you think an properly functioning immune system is for?
The same thing has happened with the pertussis vaccine, as far as lack of efficacy, and they have tried everything to include vaccinating the whole family and the parents and still the vaccine keeps failing and those vaccinated still get pertussis. Yet the CDC refuses to admit the failure of that vaccine.
And what about the fraud that has been conducted by Merck, regarding the mumps efficacy portion of the MMR vaccine? Outbreaks of mumps has been seen in the vaccinated as well.
Merck vaccine fraud exposed by two Merck virologists; company faked mumps vaccine efficacy results for over a decade, says lawsuit.
According to two whistle blowing former Merck virologists who filed a 2010 Federal False Claims Act complaint two years ago in 2010 when the Act first passed, as of June 28, 2012, the scientist's complaint at last has been unsealed. The complaint reports that the corporate pharmaceutical vaccine manufacturer, Merck allegedly "knowingly falsified its mumps vaccine test data, spiked blood samples with animal antibodies, and sold a vaccine that actually promoted mumps and measles outbreaks."
The complaint accuses Merck of allegedly ripping off governments and consumers who bought the vaccine thinking it was "95% effective.
Of course Merck denies all alleged accusations to today's breaking news report.
Look at all the trouble these vaccine producing pharmaceutical companies have been in for fraud, and how many times they have paid huge penalties. It doesnt matter to them because the profits are always far more than the fines for fraud. And these are the people you are going to trust to do proper safety studies and to provide vaccines for YOUR child? Do a search regarding fraud here on the DOJ site, for each pharmaceutical company; it is amazing what they continue to get away with.
You see if alias Costner, is not willing to take every vaccine on the current CDC schedule, himself; including the three shots of Gardasil, and/or put his own children at risk, then he has nothing to say, and it is at that point he becomes as well the major hypocrite he repeatedly and falsely accuses with the pointing finger at others. Obviously common sense tells us that you don't make others take risks you wouldn't take yourself. You say they are safe, and the controversy states they are not; simply prove it by getting all the shots yourself. Pretty simple. And you know he has to be connected to someone on the medical side, so shouldn't be a problem.
Here is the challenge he needs to take; you want to prove vaccines are safe, here is your way to prove it. Being he likely is not the weight and size of an infant, to be fair, the vaccines should be adjusted for body weight as she states in this below video by Mary Tocco. However, I would let him by with just getting all the vaccines the kids get on the same schedule; and quite obviously even that he would very likely refuse.
Insanity: is doing the same thing in the same way and expecting a different outcome.
Insta-nity: the state of becoming instantly and selectively illogical and irrational or insane.
And as for the subject matter of that blog page; what a claimed polio vaccine, success story, right? To know anything , you actually have to educate yourself to the unbiased facts; and to begin with be willing to and accepting of the facts. Costner is all about the science, but yet he can not find any to support his position, and/ or that have not been already shot 100 holes in. You can not be all about the science and then refuse to acknowledge anything but what you find acceptable, and all else is wiped off the table. To falsely claim any science to be non reputable, that clearly shows the physiological connections and mechanisms of harm by vaccines is simply intellectual dishonesty of the highest order. Anything that does not support your pro-vaccine false propaganda promoting agenda is simply swept off the table; and then with a mindless repeat claim thrown directly into the air, that YOU did not and have not show me any proof science as to the vaccine neurological harm, nor vaccines connection to ASD. The same bullshit and false information is just the own back onto the table, as THIS is the only information and data I will accept. This is again of course, the only thing allowed to be considered is the same mindless ask no questions CDC/WHO pharma connected style propaganda and false information, with no proof and no actual proof science to back it, that has been fed to us for the last 100 years. You can choose to be a brainwashed sheeple, or you can choose to actually use some common sense and critical thinking ability; and start questioning what you have been told..
Indian J Med Ethics. 2012 Apr-Jun;9(2):114-7.
Polio programme: let us declare victory and move on.Vashisht N, Puliyel J.
Source: Department of Paediatrics, St Stephens Hospital, Delhi 110054, India.
It was hoped that following polio eradication, immunisation could be stopped. However the synthesis of polio virus in 2002, made eradication impossible. It is argued that getting poor countries to expend their scarce resources on an impossible dream over the last 10 years was unethical. Furthermore, while India has been polio-free for a year, there has been a huge increase in non-polio acute flaccid paralysis (NPAFP). In 2011, there were an extra 47,500 new cases of NPAFP. Clinically indistinguishable from polio paralysis but twice as deadly, the incidence of NPAFP was directly proportional to doses of oral polio received. Though this data was collected within the polio surveillance system, it was not investigated. The principle of primum-non-nocere was violated. The authors suggest that the huge bill of US$ 8 billion spent on the programme, is a small sum to pay if the world learns to be wary of such vertical programmes in the future.
Polio Vaccine Historical Facts / The Real Truth
VRM: Polio Scam
Scientific proof that the known cancer causing SV40 virus, a previous contaminant in the polio vaccine, is obviously either contagious; or the virus is still in the vaccines.
Lack Of Aluminum Adjuvant Safety Data
SOME EFFECTS OF REDUCED CARRYING CAPACITY
Aluminum toxicity is a widespread problem in all forms of life, including humans, animals, fish, plants and trees, and causes widespread degradation of the environment and health. Over 7000 reference articles on aluminum toxicity exist in various data bases; ( as of 1996 ) all recognizing the toxicity but concluding the mechanism of action is unknown. — [ Search results - scirus.com ]
Despite the number of references to aluminum toxicity, the FDA has always exempted it from testing, by putting it on their "Generally Regarded as Safe" ( GRAS ) list. Aluminum can be added to foods, medicines or water without restriction from the FDA.
From: History of crime against the Food Laws (1929) by Dr. Riley, the prime mover behind the original Pure Food Law and Director of the FDA. He resigned in disgust in 1912 over exceptions granted to the law and lack of enforcement.
Aluminum has been exempted from testing for safety by the FDA under a convoluted logic wherein it is classified as GRAS. (Generally Regarded As Safe.) It has never been tested by the FDA on its safety and there are NO restrictions whatever on the amount or use of aluminum. Diseases Associated with Aluminium Intoxication. H. Tomlinson, M.B., Ch.B., MRCS., LRCP.
Since that time thousands of studies have been published indicating aluminum is involved in neurological dysfunction, immunocompetence, as well as a host of other morbidities.
Facts About Vaccine Aluminum Adjuvants, (with lots of real science regarding overactivation of the brains microgilia, and resulting repeat and chronic brain inflammation).
"Following Vaccinations" -- 900 Voices Telling the Truth
Parents Voice: Children’s Adverse Outcomes Following Vaccination
MMR Vaccine -Truth - The Truth Behind a Tragedy
Vaccine Caused Ischemia/Hypoxia
CDC REFUSES TO STUDY VACCINE INDUCED ENCEPHALOPATHY
If you would like to read the actual 2006 Gardasil FDA pre-approval document that has been made reference to here, luckily Natural News in approximately 2008 had saved a copy of it to their files, just in case the FDA removed it, and sure enough it appears the FDA did. Take a look, and then ask how in anyones right mind did they approve that vaccine, knowing what they knew. They also as well knew that Gardasil in the clinical trials had never been tested against a true placebo. One placebo was and contained the aluminum adjuvant, which there are over 600 mcg of aluminum adjuvant content in the combine three shots. There is also information that a second placebo used contained the carrier solution, meaning all of the vaccine ingredients, but the antigen. There is no way that situation could have carried any measure of true safety analysis.
They new as well that during the clinical trials that many girls developed new medical conditions, the same thing being seen now in 100's if not thousands of young women having received 1 to 3 shots of Gardasil; many luckily never finished it, but yet many did, and a as well did not survive. Yet the FDA and CDC continue to whitewash it all and claim there is no connection found. if they will not remove this vaccine from the market, after all the damage it has done; then what are they capable of telling the truth about, ever? Clear HPV DNA issues, the same DNA that Merck said they had removed, now known as well locked to the aluminum adjuvant, and they yet say there is no proof of a problem. Nothing would be enough, they simply have to much to lose, and they as well simply do not care what happens.They are NOT admitting to it, ever.
A little info on as well on aluminum adjuvants in regard to Gardasil.
Educate For The vaccine Injured
SANE Vax Inc. Discovers Potential Biohazard Contaminant in Merck's Gardasil™ HPV 4 Vaccine
Gardasil Scientific References and Citations
Sane Vax Video Index
The Myths Of - Vaccine - Derived - Herd Immunity
Modern Medicine-A Leading Cause Of Death
Bringing the ASD Child Back, biomedical treatment, it CAN be done; a parents story of the journey. Please pass this information on to any parent/s that need the help and this very well put together information! Reversing the ASD, while your doctor will only offer prescriptions to cover up the problem, and make sick brainwashed claims and excuses as for why the parents should not be using biomedical treatment.
Excerpt: I believe now, that a lot of her toxic burden came from me. While I was
pregnant with her I had 2 rhogam shots, surgery for a an appendicitis, dental
work done, and I have hypothyroidism. I also had her by c-section. She was
born in November of 2001 so I am pretty sure she had the vaccines with the
(Any toxic overload)
Recovering Kids. com
Advances in Biomedical Research
Stan Kurtz, recovery videos
You see there are heroic thinking people out there that after their own child was through it, choose to help other parents out of that ASD nightmare. It is the damn vaccines, as a fact.
Several babies died of SIDS in N. Idaho in the Fall of 2007. One family shares the story of their son who died 3 days after being vaccinated.
Baby Dies After 9 Vaccines in One Day
Baby dies just days after immunizations
Adverse reaction and Death after MMR Vaccine, (listen to that, all they were concerned about was a media crisis)
Mother Explains Vaccine Injury, Deteriorating Health, Autism, and Why Not To Vaccinate
Autistic Child Fully Recovered with Biomedical Treatment for Autism - Holly Riley
Autism Is A Medical Problem And There Is Proven, Effective Medical Treatment - Dr. Stoller, MD (former pediatrician with the American Academy of Pediatrics)
"No Evidence of Any Link" 58 studies
Public School Exemptions
Vaccine Package Inserts
How a baby fights infection and develops the immune system
Why Vaccines Are Scientific Fraud
You will notice from these three charts, that in each and every case, the epidemic was already decreasing dramatically – long before the vaccine was ever introduced!
Note also that in medical textbooks, the chart showing the decline in the polio death rate is only shown from the point of the first red line forward! This leads medical and nursing students to erroneously believe that the polio vaccine was responsible for the decline in the disease which is simply not true! As you can see from the chart, polio was already well on its way out before the vaccine which is the same story shown in the charts for pertussis (whooping cough) and measles as well as other infectious diseases that didn’t have vaccines.
Phage in Live Virus Vaccines: Are They Harmful to People? (Phage is NOT only in live vaccine virus vaccines).
Science 14 February 1975:
Autism Epidemic, Is Foreign DNA in MMR II Vaccine Responsible? CBCD Suggests CDC Study Microcompetition Theory
The Center for the Biology of Chronic Disease (CBCD) believes that the cause of the epidemic is the foreign DNA in the MMR II vaccine.
Foreign DNA Fragments Cause Major Diseases
Pro-Vaccine Immunologist Admits a Shocking Truth About Vaccines
Posted on October 31, 2011
For several years, until April of this year, I had been lecturing nationally to health professionals about the great vaccine hoax. Attending one such seminar was a board member of an association of health professionals, who invited me to speak on this subject at their national conference. I did, and had 90 minutes to present the most salient points from my 7-hour seminar. It caused quite a stir, and several clinicians thanked me for having the courage to speak the truth about this controversial subject.
Later that day, I sat on a panel of four experts to answer questions from conference attendees. Many of the questions were directed at the PhD immunologist on the panel, asking if the statements I had made in the morning presentation were true. To my surprise, the immunologist confirmed every assertion I had made.
The first was that it is pointless to administer drugs intended to stimulate antibody production to babies who are too young to produce antibodies. Infants in their first year mostly depend on generalized, non-specific immunity, including (hopefully) immunoglobulins from breast milk, to protect their young bodies from infection. They do not produce antibodies of their own until about age one. Despite this basic fact, the medical establishment insists administering a total of 19 shots, containing 24 vaccines, to infants on the 2, 4 and 6 month pediatric visits (Source: cdc.gov). Somehow, the basic facts of human physiology and development do not apply to vaccines.
Series Two: Clinical Seminars for Health Professionals
Success with Natural MedicineTM:
Integrating Whole Food Concentrates & Western Herbs into Clinical Practice
Group Two: Clinical Topic Seminars: In-depth education on essential clinical areas
Vaccination Alternatives and Preventing Infectious Disease
Mass immunizations are widely touted by conventional medicine and the mainstream media as being responsible for eradicating and preventing many infectious diseases. There is much debate as to the accuracy of this view, considering the fact that all immunized diseases were mostly gone by the time mass vaccination to those diseases was implemented. At the very least, there is great concern whether the claimed benefits outweigh potential dangers and adverse reactions. Vaccines, heavily marketed as essential prevention for babies, adolescents, adults and the aged, have proven to be ineffective for preventing disease and in are many cases harmful, particularly as compared to improved nutrition, hygiene and sanitation. These three factors, combined with the acquired mass immunity to microbes over time, are the factual reasons for the near-eradication of the immunized diseases.
This eye-opening seminar presents objective data on the history, questionable efficacy and inconsistent safety of vaccine programs. Special attention is also given to the completely ineffective and potentially disastrous flu shot. The lecture goes on to train clinicians in using safe, effective and practical tools for improving the immune health of their patients. Particular emphasis is given to diet, lifestyle and natural medicine for preventing infectious disease, and supporting patients with acute infections.
Long-term persistence of vaccine-derived aluminum hydroxide is associated with chronic cognitive dysfunction
Pathophysiological mechanisms underlying MACD remain to be determined. In conclusion, long-term persistence of vaccine-derived aluminum hydroxide within the body assessed by MMF is associated with cognitive dysfunction, not solely due to chronic pain, fatigue and depression.
SafeMinds: New Scientific Evidence Links Autism to Vaccines and Mercury
Nanomolar aluminum induces pro-inflammatory and pro-apoptotic gene expression in human brain cells in primary culture
Walter J. Lukiw a,*, Maire E. Percy b, Theo P. Kruck b
a Neuroscience Center of Excellence and Department of Ophthalmology, Louisiana State University Health Sciences Center,
2020 Gravier Street, Suite 8B8, New Orleans, LA 70112-2272, USA
b Neurogenetics Laboratories, Surrey Place Center and Center for Research in Neurodegenerative Disease, Tanz Neuroscience Center, University of Toronto, Toronto, Ont., Canada M5S 1A8
Received 23 March 2005; received in revised form 19 April 2005; accepted 20 April 2005
The promoters of genes up-regulated by aluminum are enriched in binding sites for the stress-inducible transcription factors HIF-1 and NF-kappaB, suggesting a role for aluminum, HIF-1 and NF-kappaB in driving atypical, pro-inflammatory and pro-apoptotic gene expression. The effect of aluminum on specific stress-related gene expression patterns in human brain cells clearly warrant further investigation.
Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells.
Alum (aluminum hydroxide) is the most widely used adjuvant in human vaccines, but the mechanism of its adjuvanticity remains unknown. In vitro studies showed no stimulatory effects on dendritic cells (DCs). In the absence of adjuvant, Ag was taken up by lymph node (LN)–resident DCs that acquired soluble Ag via afferent lymphatics, whereas after injection of alum, Ag was taken up, processed, and presented by inflammatory monocytes that migrated from the peritoneum, thus becoming inflammatory DCs that induced a persistent Th2 response. The enhancing effects of alum on both cellular and humoral immunity were completely abolished when CD11c+ monocytes and DCs were conditionally depleted during immunization. Mechanistically, DC-driven responses were abolished in MyD88-deficient mice and after uricase treatment, implying the induction of uric acid. These findings suggest that alum adjuvant is immunogenic by exploiting “nature's adjuvant,” the inflammatory DC through induction of the endogenous danger signal uric acid.
[These findings suggest that alum adjuvant is immunogenic by exploiting “nature's adjuvant,” the inflammatory DC through induction of the endogenous danger signal uric acid.]
[Does THAT sound like it would be healthy, and/or that it would promote good health, and strong properly functioning immune system?] (Of course not).
DNA released from dying host cells mediates aluminum adjuvant activity
Furthermore, we propose that host DNA signaling differentially regulates IgE and IgG1 production after alum-adjuvanted immunization. We suggest that, on the one hand, host DNA induces primary B cell responses, including IgG1 production, through interferon response factor 3 (Irf3)-independent mechanisms. On the other hand, we suggest that host DNA also stimulates 'canonical' T helper type 2 (TH2) responses, associated with IgE isotype switching and peripheral effector responses, through Irf3-dependent mechanisms. The finding that host DNA released from dying cells acts as a damage-associated molecular pattern that mediates alum adjuvant activity may increase our understanding of the mechanisms of action of current vaccines and help in the design of new adjuvants.
[And they deny that vaccines dysregulate the immune system and cause allergy?]
Aluminum-based adjuvants (aluminum salts or alum) are widely used in human vaccination, although their mechanisms of action are poorly understood. Here we report that, in mice, alum causes cell death and the subsequent release of host cell DNA, which acts as a potent endogenous immunostimulatory signal mediating alum adjuvant activity. Furthermore, we propose that host DNA signaling differentially regulates IgE and IgG1 production after alum-adjuvanted immunization. We suggest that, on the one hand, host DNA induces primary B cell responses, including IgG1 production, through interferon response factor 3 (Irf3)-independent mechanisms. On the other hand, we suggest that host DNA also stimulates ‘canonical’ T helper type 2 (TH2) responses, associated with IgE isotype switching and peripheral effector responses, through Irf3-dependent mechanisms.
The finding that host DNA released from dying cells acts as a damage-associated molecular pattern that mediates alum adjuvant activity may increase our understanding of the mechanisms of action of current vaccines and help in the design of new adjuvants.
Cutting Edge: Alum Adjuvant Stimulates Inflammatory Dendritic Cells through Activation of the NALP3 Inflammasome
We propose that, in addition to TLR stimulators, agonists of the NALP3 inflammasome should also be considered as vaccine adjuvants.
[So obviously they think that chronic inflammation in the body and brain is a necessary, good, and healthy thing, to stay healthy and free of disease? Mindless!!!!
Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity
As an approved vaccine adjuvant for use in humans, alum has vast health implications, but, as it is a crystal, questions remain regarding its mechanism. Furthermore, little is known about the target cells, receptors, and signaling pathways engaged by alum. Here we report that, independent of inflammasome and membrane proteins, alum binds dendritic cell (DC) plasma membrane lipids with substantial force. Subsequent lipid sorting activates an abortive phagocytic response that leads to antigen uptake. Such activated DCs, without further association with alum, show high affinity and stable binding with CD4+ T cells via the adhesion molecules intercellular adhesion molecule-1 (ICAM-1) and lymphocyte function–associated antigen-1 (LFA-1). We propose that alum triggers DC responses by altering membrane lipid structures. This study therefore suggests an unexpected mechanism for how this crystalline structure interacts with the immune system and how the DC plasma membrane may behave as a general sensor for solid structures.
[More disregard for inflammation, as if it has no adverse effect on general health.]
(So what is the real truth in and from these studies? One study states yes and one yes; and one that it stimulates quote: We propose that, in addition to TLR stimulators, agonists of the NALP3 inflammasome should also be considered as vaccine adjuvants. unquote. So, do aluminmum adjuvants stimulate dendritic cells, or NOT? They have used aluminum adjuvants since the 1930's; the FDA as well having given substance aluminum a s status of (GRAS), generally regard as safe, in 1929. And still today in 2012 ther have been no safety studies nor does any safety data exist, as to aluminum vaccine adjuvants. To date as well, if you look, there still seems be a general consensus at the CDC, that they do not yet even fully undertand how an aluminum adjuvant works, in boosting the immune response. And they claim to have all the science?)
Here in another study we this below, being stated:
3-10 The Toll-Like Receptor Family of Innate Immune Receptors
Recognition of conserved microbial components by Toll-like receptors leads to inflammation and activation of sentinel immune cells
Stimulation of macrophages or mast cells through their Toll-like receptors
leads to the synthesis and secretion of proinflammatory cytokines and lipid mediators, thereby
initiating the inflammatory response that recruits both soluble immune components and
immune cells from the blood, and which we describe in later sections. TLR stimulation of
dendritic cells induces the initiation of an adaptive immune response, as we shall see in the
next chapter. In this section and the next we shall focus on the structural and functional
features of this family of receptors that enable it to detect the presence of infection and to
signal an appropriate response.
(Any way you look at it, this is NOT a normal nor a healthy thing nor chain of events within going on within the human body).
Aluminum Is a Potential Environmental Factor for Crohn’s Disease Induction
Pediatric Gastroenterology and Nutrition Unit, Carmel Medical Center,
Pappaport School of Medicine, Technion-Israel Institute of Technology, Haifa,
Al immune activities share many characteristics with the immune pathology of CD: increased antigen presentation and APCs activation, many luminal bacterial or dietary compounds can be adsorbed to the
metal and induce Th1 profile activity, promotion of humoral and cellular immune responses, proinflammatory, apoptotic, oxidative activity, and stress-related molecule expression enhancement, affecting intestinal bacterial composition and virulence, granuloma formation, colitis induction in an animal model of CD, and terminal ileum uptake.
Autoimmune or auto-inflammatory syndrome induced by adjuvants (ASIA):
Old truths and a new syndrome?
Pier Luigi Meroni a,b,*
a Chair and Division of Rheumatology, Istituto G. Pini, Milan, Italy
b IRCCS Istituto Auxologico Italiano, Milan, Italy
Self-Organized Criticality Theory of Autoimmunity
Systemic autoimmunity appears to be the inevitable consequence of over-stimulating the host's immune ‘system’ by repeated immunization with antigen, to the levels that surpass system's self-organized criticality.
Lupus. 2010 Apr;19(4):354-8.
Autoimmunity, infection and adjuvants.
Journal of Neuroimmunology
Volume 238, Issue 1 , Pages 73-80, 15 September 2011
The effect of infection in initiating autoimmune disease has been debated for many years. There are, even now, few instances of a human autoimmune disease clearly caused by prior infection, probably due to the frequent separation in time and space from the clinical outcomes. As our understanding of the immunologic consequences of the infectious process has deepened, we can re-think some of the issues by focusing attention on the varied adjuvant effects of microbial products. We are now able to distinguish some of the critical steps in progression from virus infection to benign autoimmunity to autoimmune disease in an experimental model of myocarditis. Immune regulators, such as cytokines and costimulatory molecules, serve as signposts in the process. The lessons learned may be broadly applicable to autoimmune disorders.
Children with autism spectrum disorders (ASD) who exhibit chronic gastrointestinal
(GI) symptoms and marked fluctuation of behavioral symptoms exhibit distinct
innate immune abnormalities and transcriptional profiles of peripheral blood
Harumi Jyonouchi a,⁎, Lee Geng a, Deanna L. Streck b, Gokce A. Toruner b
a Division of Allergy/Immunology and Infection Diseases, Department of Pediatrics, University of Medicine and Dentistry of New Jersey (UMDNJ)-New Jersey Medical School (NJMS),
185 South Orange Ave, Newark, NJ, United States
b Institute of Genomic Medicine, Department of Pediatrics, University of Medicine and Dentistry of New Jersey (UMDNJ)-New Jersey Medical School (NJMS), 185 South Orange Ave,
Newark, NJ, United States
Innate/adaptive immune responses and transcript profiles of peripheral blood monocytes were studied in ASD children who exhibit fluctuating behavioral symptoms following infection and other immune insults (ASD/Inf, N=30). The ASD/Inf children with persistent gastrointestinal symptoms (ASD/Inf+GI, N=19), revealed less production of proinflammatory and counter-regulatory cytokines with stimuli of innate immunity and marked changes in transcript profiles of monocytes as compared to ASD/no-Inf (N=28) and normal (N=26) controls. This included a 4–5 fold up-regulation of chemokines (CCL2 and CCL7), consistent with the production of more CCL2 by ASD/Inf+GI cells. These results indicate dysregulated innate immune defense in the ASD/Inf+GI children, rendering them more vulnerable to common microbial infection/dysbiosis and possibly subsequent behavioral changes.
And where would that kind of disregualtion likely come from; other than from multiple toxic vaccines?
J Neuroinflammation. 2012 Jan 7;9:4.
Immunological characterization and transcription profiling of peripheral blood (PB) monocytes in children with autism spectrum disorders (ASD) and specific polysaccharide antibody deficiency (SPAD): case study.
The Immunological findings in the ASD/SPAD children who exhibit fluctuating behavioral symptoms and cognitive skills cannot be solely attributed to SPAD. Instead, these findings may be more specific for ASD/SPAD children with the above-described clinical characteristics, indicating a possible role of these immune abnormalities in their neuropsychiatric symptoms.
Cellular networks controlling Th2 polarization in allergy and immunity
Th2 cell immunity is something of a two-edged sword. These cells evolved to fight off parasites, but they are also responsible for allergic diseases. Recent advances in understanding Th2 immunity bring us closer to more effective treatments for allergic diseases like allergic asthma and rhinitis, atopic dermatitis and food allergy. These are clearly on the rise in western societies, and pose a significant burden on the health of millions of patients and on health expenditure.
The immune system evolved to neutralize or kill invading pathogens, while at the same time avoiding reactivity to self, harmless commensal organisms and environmental antigens like allergens. Most often, pathogens are neutralized through the effector mechanisms of innate immunity, such as the activation of complement, and phagocytosis and/or killing by macrophages, neutrophils or eosinophils. These innate responses are reinforced by adaptive immunity, in that humoral immunity facilitates complement activation and phagocytosis by innate immune cells and that particular subsets of T lymphocytes help innate effector cells through release of cytokines.
THE ROLE OF DENDRITIC CELLS IN DIFFERENT TH2 MODELS
Dendritic cells perform a unique sentinel function in the immune response in that they recognize antigens through expression of ancient pathogen pattern recognition receptors (PRRs), such as Toll-like receptors (TLRs), NOD-like receptors, and C-type lectin receptors. These receptors will recognize motifs on virtually any pathogen, allergen, or substance. In addition, dendritic cells have been shown to be sensitive to more generic stress responses, such as oxidative stress, increased rates of protein synthesis and hypoxia, that could also signal the presence of xenobiotics, local tissue injury and disturbance of homeostasis [5,6]. Dendritic cells take up, process and present antigens on their surface, and posses the ability to migrate from the tissues to the draining lymph node. Having all these capabilities, dendritic cells are at the crossroads between innate and adaptive immunity .
(And the science of vaccinology and immunology, can not comprehend that vaccines and multiple vaccines are screwing with all of this and these human physiological systems, in a major way; creating far more harm than good? And they see food and environmental allergies increasing in the children and as well asthma, but they do not find that in the un-vaccinated, they they stand there clueless as to the cause, and would tell you they dont know the cause, but they know its NOT vaccines??? How mindless in denial, is that?)
Inflamm Allergy Drug Targets. 2012 Jun 8. [Epub ahead of print]
Non-IgE mediated food allergy update of recent progress in mucosal immunity.
Source:Division of Allergy/Immunology and Infectious Diseases, Department of Pediatrics, University of Medicine and Dentistry of New Jersey- New Jersey Medical School, Newark, NJ, United States.
As opposed to IgE mediated food allergy (IFA) which can cause fatal outcomes, non-IgE mediated FA (NFA) was initially thought to be a benign condition mediated by cellular immune responses, primarily affects the GI mucosa. NFA children were thought to recover well upon avoidance of offending food. Although pathogenesis of NFA is still not well understood, recent studies indicate widely variable clinical manifestations of NFA. In parallel to our better appreciation of clinical features of NFA, complex regulatory mechanisms of gut immune homeostasis have become known with progress in our understanding of the gut mucosal immune system. In addition, a role of gut commensal flora on the gut immune system has also become better understood along with the effects of dietary components. Subtle changes in interactions between environmental factors (microbiota, dietary components, etc) and the gut immune responses can affect gut immune homeostasis, which can result in undesired adverse reactions to food proteins (FPs). This review discusses recent progress in our understanding of the regulatory mechanisms of gut immune homeostasis and recently revealed widely variable clinical presentations of NFA with respect to it pathogenesis.
Expert Rev Clin Immunol. 2010 May;6(3):397-411.
Autism spectrum disorders and allergy: observation from a pediatric allergy/immunology clinic.
Curr Allergy Asthma Rep. 2009 May;9(3):194-201.
Food allergy and autism spectrum disorders: is there a link? (And what caused the food allergy, that you do not see in the un-vaccinated, or very rarely?)
http://wwAnd again pointing to vaccines as the only likely source of causation for that kind of immune system dysregulation; and most of these children were entirely healthy prior to vaccines.
J Neuroinflammation. 2008 Nov 21;5:52.
Impact of innate immunity in a subset of children with autism spectrum disorders: a case control study.
Clinical features of the ASD test group were not associated with atopy, asthma, FA, or PID in our study but may be associated with altered TLR responses mediating neuro-immune interactions.
Again, all is caused by an altered from normal, dysregualtion of the immune function! Vaccines as toxic as they are, can't cause that? And with no existing safety studies they can claim to that, as a fact? They have done no physiological safety studies, even on aluminum adjuvants, nor even any CDC funded epidemiological studies. They have claimed to have only studied with epidemiologal (population) studies, one vaccine, the MMR, and one vaccine ingredient, thimerosal. All else was off the tabel. There is the extent of their safety research. And they say all the needed scicne is in, and to look no further? And, as well is advised to; "Don't be an internet mom"? Be a sheeple, AND QUESTION NOTHING. Nothing in their mind ever points to vaccines, nor ever would; because they simply refuse to see it.
Anti-NMDA-Receptor Encephalitis Added to DSM A Medical Causation of Autism
N-methyl D-aspartate receptor encephalitis: A new addition to the spectrum of autoimmune encephalitis
Eur Child Adolesc Psychiatry. 2012 Mar;21(3):141-7. Epub 2012 Feb 10.
Presence of GAD65 autoantibodies in the serum of children with autism or ADHD.
Rout UK, Mungan NK, Dhossche DM.
But they KNOW its NOT the vaccines, right?
Neuroscience. 2010 Dec 29;171(4):1075-90. Epub 2010 Oct 20.
Role of the NR2A/2B subunits of the N-methyl-D-aspartate receptor in glutamate-induced glutamic acid decarboxylase alteration in cortical GABAergic neurons in vitro.
But its proven by the CDC funded epidemiological studies to not be the vaccines, right? No matter how many children are recovered by the use of proper biomedical treatment and detoxification.
Advances in Biomedical Research
GAD65, Diabetes, Autoimmunity And Autism
Autism and Glutamate Dysfunction - Avoid The Cause - Race To The Cure
Pediatrics. 2010 Jan;125 Suppl 1:S1-18.
Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: a consensus report.
Care providers should be aware that problem behavior in patients with ASDs may be the primary or sole symptom of the underlying medical condition, including some gastrointestinal disorders. For these patients, integration of behavioral and medical care may be most beneficial. Priorities for future research are identified to advance our understanding and management of gastrointestinal disorders in persons with ASDs.
So, why are they not doing it, and that; instead of making denial of the success of biomedical treatment and in regard to dietary restrictions that heal the said damaged gut and digestive tract in these children? A protocol that has alone reversed ASD in numerous children. Answer as to why; forst it implicated vaccines which they are not going to allow to happen; second, it is a non drug/pharmaceutical approach; and the FDA states that nothing can cure nor prevent a disorder and disease but a pharmaceutical drug. If you claim a supplement has any sort of health benefit in the reversal of any health condition, it is shut down by the FDA, as any such claims cause the product or spplement to thus become a drug, and has not been approved through millions of dollars in clinical trials. Thus their failed pharma system maintains a complete monopoly on so called health care. Thus the hospitals and systems only become bigger, and with more children hopsitals being built on the false premise of being the ultimate saviors in existence. The whole thing is for profit and control, SICK! This is and was what they have built, for the past 100 years, and nothing can stop it; nor the brainwashed and evil insanity of it all.
And mainstream has recieved millions in research money to look at causation and treatent of ASD, and they are NOT looking at any of the alternative studies, other than within the mindset that the CDC accepts and has allowed to be considered. It is clearly and obviously all controlled. What do you think would happen to any research even indirectly pointing a finger at vaccines? Do you actually think it would get more funding, and the researchers praised for their innovative and pioneering good work?? Not a chance.
How a baby fights infection and develops the immune system
Vaccines and neonatal immune development
Can vaccines become cranial and immunological cluster bombs?
PLoS One. 2008;3(11):e3815. Epub 2008 Nov 26.
Mitochondrial disease in autism spectrum disorder patients: a cohort analysis.
Although all patients' initial diagnosis was idiopathic autism, careful clinical and biochemical assessment identified clinical findings that differentiated them from children with idiopathic autism. These and prior data suggest a disturbance of mitochondrial energy production as an underlying pathophysiological mechanism in a subset of individuals with autism.
A few useful references re mitochondrial issues in autism:
(Series, Part 1 of 3) The Scientist recently published an article about Dr Douglas Wallace who is head of a new unit called the Center for Mitochondrial and Epigenomic Medicine, at the Children’s Hospital of Philadelphia. Dr Wallace believes that “Every one of the diseases we can’t solve is absolutely logical if we put energy at the center,” ... “I believed that in 1970 and I believe it now.” So what’s a mitochondria?
Does mitochondrial dysfunction lie at the heart of common, complex diseases like cancer and autism?
Ever wonder what's listed as a side effect to the vaccine you just gave your child? Maybe wanna know who manufactured it? Click on the vaccines below for manufacturer package inserts that you should LEGALLY be given when receiving any vaccine.
Infanrix HEP B FDA Advisory Meeting Transcript 2001- with NVIC's Barbara Loe Fisher
The Association of Vitamin D Status With Pediatric Critical Illness
CONCLUSIONS: This study provides evidence that vitamin D deficiency is both common among critically ill children and associated with greater severity of critical illness. Further research will determine whether targeted vitamin D supplementation or rapid restoration will improve outcome.
Pediatrics Digest Summary
Vitamin D Deficiency in Critically Ill Children
Vitamin D is essential for bone health and for cardiovascular and immune function. In critically ill adults, vitamin D deficiency is common and associated with sepsis and with higher critical illness severity. The influence on pediatric critical illness is unclear.
We found a high prevalence of vitamin D deficiency in critically ill children, which was associated with higher critical illness severity. Vitamin D deficiency was less common in younger patients, in non-Hispanic white patients, in patients admitted over the summer, and in children taking supplemental vitamin D, with increasing amounts being more protective. (Read the full article)
Vitamin D Deficiency in Critically Ill Children
CONCLUSIONS: We found a high rate of vitamin D deficiency in critically ill children. Given the roles of vitamin D in bone development and immunity, we recommend screening of those critically ill children with risk factors for vitamin D deficiency and implementation of effective repletion strategies.
So why are no pediatricians promoting vitamin D? So why are they vaccinating without giving a thought to vitamin D deficiency? Because vitamin D3 the proper form, opposed to the unnatural toxic and ineffective D2, is not a patentable pharma drug. Only drugs and vaccines can cure or prevent disease, FDA. WHAT have they actually cured, and what have they actually and in the long term, prevented?
The pH Miracle
And how much science has Costner ever had, and as well as to in regard to causation of ASD? A pittance of scant theories that only at best pertain to a small minority of children; that, if ever determined as fact.